©1996-2008
All Rights Reserved. Online Journal of Bioinformatics . You may not store these pages in
any form except for your own personal use. All other usage or distribution is
illegal under international copyright treaties. Permission to use any of these
pages in any other way besides the before
mentioned must be gained in writing from the publisher. This article is
exclusively copyrighted in its entirety to OJB publications. This article may
be copied once but may not be, reproduced or re-transmitted
without the express permission of the editors. This
journal satisfies the refereeing requirements (DEST) for the Higher Education
Research Data Collection (Australia). Linking:To link to this page or any pages linking to this page
you must link directly to this page only here rather than put up your own page.
OJBTM
Online Journal of Bioinformatics ©
Volume 9 (2): 113-120, 2008
Homology based 3D–structure modeling of glucose specific Sesbania
stem lectin.
Saxena S, Das HR,
Das D, Biswas S
Proteomics and Structural Biology Laboratory,
Institute of Genomics and Integrative Biology,
ABSTRACT
Saxena S, Das HR, Das D, Biswas
S, Homology based 3D–structure modeling of
glucose specific Sesbania stem lectin. Online Journal of Bioinformatics, 9 (2)
113-120, 2008. The lectins from legumes show a considerable sequence and
structural homology but their differences in carbohydrate specificity make them
unique for studying structure function relationships. 3D models of proteins
were created to evaluate crystal structure and function
relationships. The 3D model of Sesbania bispinosa stem lectin (STA) (Accession No.ABX59683.1)
was vizualised using web server Geno3D. Stereochemical
properties were analyzed using PROCHECK and generated
models visualized with Rasmol 3D viewer and MolProbity for X-ray crystallography. This study describes
computer generated molecular models for which crystal structures are not
available.
Keywords: Homology modeling, Geno
3D, MolProbity, Lectins, Sesbania
FULL-TEXT(SUBSCRIPTION
and SINGLE FULL-TEXT ARTICLE)