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OJVRTM

 

 Online Journal of Veterinary Research©

  Volume 11 (1) : 39-45, 2007

Ketamine-xylazine/tiletamine-zolazepam prolonged anesthesia in Cynomolgus monkeys.

 

Cheah PS1, Low CK2,Mohidin N3, Bariah MA3, Maung M1, Azian AL1

 

1Department of Anatomy, Faculty of Medicine, 2Laboratory Animal Resource Unit, Faculty of Medicine3 Department of Optometry, Faculty of Allied Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia.

ABSTRACT

 

Cheah PS, Low CK,Mohidin N, Bariah MA, Maung M, Azian AL Ketamine-xylazine/tiletamine-zolazepam prolonged anaesthesia in Cynomolgus monkeys. Online JournaL of Veterinary Research 11 (1) : 39-45, 2007. The physiological effects of a mixture of ketamine, xylazine, tiletamine and zolazepam (KT/XZ), in cynomolgus monkeys during 24 hr anesthesia is described. Eight were induced with ketamine IM and anesthetized with IV KT/XZ. In all, anesthesia was maintained for 24 hours with large decreases in rectal temperature, heart and respiratory rates but moderate hypotension. All monkeys recovered normally 4 hours post-anesthesia. These results suggest that KX/TZ mixture could be used for prolonged anesthesia in cynomolgus monkeys.

 

Keywords  ketamine-xylazine, tiletamine-zolazepam, cynomolgus monkey, anesthesia

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