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OJVRTM

Online Journal of Veterinary Research©

  Volume 12 (1) :1-6, 2008


Spontaneous hepatocellular carcinoma in a Syrian hamster

 

Ghaffari MS1, Dezfoulian O2

 

 

1Department of Clinical Sciences, Faculty of Veterinary Medicine, Islamic Azad University- Karaj Branch and, 2Department of Veterinary Pathology, Faculty of Veterinary Medicine, University of Tehran. Tehran- Iran. 


ABSTRACT 

Ghaffari MS, Dezfoulian O, Spontaneous hepatocellular carcinoma in a Syrian hamster,  Online J Vet Res, 12 (1): 1-6, 2008. A 5-month-old female Syrian hamster was presented with a history of anorexia, weight loss, and progressive abdominal enlargement. Lateral view of the abdominal radiograph showed substantial loss of intra-abdominal contrast. Further investigation and diagnostic procedures was rejected by the owner. However, a necropsy was performed and the gross pathological findings included ascites, hepatomegaly and small hepatic cysts. The tumor was histopathologically diagnosed as hepatocellular carcinoma (HCC). To the best of the authors` knowledge, regarding the low incidence rate of spontaneous neoplasia in hamsters, this is first report of natural development of hepatocellular carcinoma in a Syrian hamster.

Key-Words: Carcinoma, hamster


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