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 Online Journal of Veterinary Research©

  Volume 11 (1) : 54-74, 2007

Vitamin C and cadmium toxicity in fish Oreochromis niloticus

 

Abbas HHH1, Hammada MM2 , Miller, JD

 

1 Hydrobiology Department, Veterinary Research Division, National Research Center El-Bohooth St. Dokki, Giza, 2 3American University in Cairo, Tahrer Square, Cairo, Egypt.

ABSTRACT

 

Abbas HHH, Hammada MM , Miller, JD Vitamin C and cadmium toxicity in fish Oreochromis niloticus Online Journal of Veterinary Research 11 (1) : 54-74, 2007. This study was undertaken to evaluate the impact of short-term exposure to cadmium and the inhibitory effect of ascorbic acid (vitamin C) on cadmium toxicity on some selected physiological and biochemical aspects of the freshwater Nile tilapia, Oreochromis niloticus. Three fish groups were exposed to 1/10 LC50 Cd, 1/10 LC50 + 500mg/L vitamin C, and 1/10 LC50 + 1000mg/L vitamin C, respectively. Fish exposed to Cadmium revealed disturbances in blood constituents and bioaccumulation of cadmium in vital organs, and a negative effect on the growth rate, meat quality and blood physiology of Nile tilapia. However, fish exposed to the same concentration of cadmium supplemented with vitamin C showed significant differences in the values of growth rates, meat quality and other physiological and biochemical parameters when compared to control. Histological examination revealed damage to gills and liver of fishes exposed to cadmium. In comparison, the histological sections of the same organs of fish supplemented with vitamin C showed that these organs were normal.

 

Key words: Toxicology, Vitamin C, Nile tilapia, Physiology, Histopathology.

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